Her music incorporates elements of pop, rock, folk, country and blues. She has released eight studio albums, two compilations, a live album and has contributed to a number of film soundtracks. She has sold more than 50 million albums worldwide. Crow has garnered nine Grammy Awards (out of 32 nominations) from the National Academy of Recording Arts and Sciences.

In addition to her own work, Crow has performed with the Dixie Chicks, the Rolling Stones, Jerry Lee Lewis, Stevie Nicks, Michael Jackson, Steve Earle, Prince, Eric Clapton, Luciano Pavarotti, Willie Nelson, Smokey Robinson, John Mellencamp, B.B. King, George Strait, Tony Bennett, Kid Rock and Sting, among others. She has also performed backing vocals for Tina Turner, Don Henley, Stevie Nicks, Belinda Carlisle, Bob Dylan and Joe Cocker.

As an actress, Crow has appeared on various television shows including 30 Rock, Cop Rock, GCB, Cougar Town, Jon Stewart and Stephen Colbert’s Rally to Restore Sanity and/or Fear, as well as One Tree Hill.